Release date: 2016-09-05
For children with autism and a class of hereditary diseases, ultrasound exposure during the first trimester of pregnancy can increase the severity of autism, according to the University of Washington School of Medicine, the University of Washington, Poser, and the Seattle Children's Institute. Research by personnel.
The study, published in the Autism Study on September 1, examined changes in symptoms of children with autism who have unknown causes. They found that exposure to diagnostic ultrasound during the first trimester of pregnancy increased the severity of autism symptoms. Children with genetic variation are most affected by autism; 7% of children in the study have these changes.
The diagnostic ultrasound currently recommended by the FDA guidelines is for essential medical use only.
“I believe our findings are sufficient to instigate FDA guidelines,†said communication author Pierre Murad, a professor of neurosurgery and engineering and mathematics at the University of Wisconsin in Seattle, Seattle, specializing in ultrasound and brain transformation studies.
Murad said that their results are related to the first trimester of pregnancy. The data effects of the second and third trimester ultrasound examinations showed no correlation, he said.
The researchers used data from Simmons' simple collection of autism gene pools funded by the Simmons Foundation Autism Research Program. The data came from 2,644 families across 12 research sites in the United States.
“We have been wondering why so many children have autism,†said first author Sarah Weber, UW Medical Psychiatry and Behavioral Researcher. "Where is the disease coming from? How is the child's autism developing? And the second question is, why do children's autism are so different from each other? This study really focuses on the second problem. With autism Among the children, what factors may cause some children to suffer more and continue to struggle for the whole life, while others have good endings or higher IQ, or better language or less seriousness? "
Weber said the research team is based on a three-part model to study the differences in symptoms of children with autism. The first one is a hereditary one. Second, it is an external source of stress. The third is the blow of the external pressure source at a certain time.
Several external pressures described by Weber have been suggested to be associated with the effects of autism. This study only studied one of them - ultrasound.
As the mother of two children, Weber said to her that she now knows that she will not undergo an ultrasound examination during the first trimester of pregnancy unless there is a medical need, including knowing the progress of pregnancy.
"If we can use other means or this information, I will choose another method," she said. “It is worth considering that the medical procedures we do have great benefits but are also dangerous.â€
Early research
In an earlier study, Murad and co-authors Weber, Abbie McClintic (UW Medical Neurosurgery Researcher) and Bryan King, Professor of Psychiatry at the University of California, San Francisco, published in the paper "Autism Research" in 2014. Intrauterine ultrasound exposure results in mice exhibiting symptoms of autism.
Murad said that he and his colleagues intend to look more closely at the severity of ultrasound and autism, and the link between the possibilities - so far has not been shown - ultrasound irradiation increases the incidence of autism.
The study was supported by the National Institutes of Health (RO1HD064820 and P50HD055782 Weber) and the Simons Simplex Collection (SFARI #89368).
Source: Noble
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