State Food and Drug Administration reminds rational use of quinolones

Business Club January 24th

Recently, the State Food and Drug Administration issued the "Information Bulletin on Adverse Drug Reactions," and the adverse reactions of the 13 quinolone drugs deserved special attention.

The 13 drugs reported this time are ofloxacin, ciprofloxacin, fleroxacin, lomefloxacin, norfloxacin, pefloxacin, enoxacin, moxifloxacin, and tosufloxacin. Pashacin, reuploxacin, pazufloxacin and pipemidic acid. Adverse reactions in severe cases are mainly systemic damage, neurological and psychiatric system damage, and damage to the skin and its attachments. In addition, the adverse reactions of the digestive system, urinary system, and respiratory system are also relatively high. At present, the unreasonable clinical use of these drugs still exists, and the irrational drug use of some drugs is more serious. For example, moxifloxacin superindicator is used in urinary system infections, gynecological diseases, and biliary tract diseases, and the proportion is more than 30%.

The State Food and Drug Administration puts forward suggestions for the safe use of such drugs: doctors should strictly grasp the indications, understand in detail the usage and dosage of drugs, contraindications and other relevant information, and rational use of quinolones. Patients with special physique should be used with caution. Patients with renal dysfunction, elderly patients should pay attention to adjust the dosage. The use of such drugs should pay attention to drinking more water and avoiding the sun.