Release date: 2009-04-03
At the 2009 China Interventional Cardiology Congress (CIT), new clinical data was presented showing that patients with coronary artery disease who received the next-generation everolimus-eluting stents experienced a 45% reduction in major cardiovascular events over two years, compared to those with first-generation paclitaxel-eluting stents. These events included cardiac death and heart attacks, marking a significant improvement in patient outcomes.
Each year, approximately 150,000 patients in China undergo stent implantation to treat coronary heart disease. However, there has been ongoing debate within the medical community regarding the long-term safety and effectiveness of these devices. During the CIT conference, two independent randomized trials—SPIRIT II and SPIRIT III—were presented, along with meta-analysis results from a global study involving over 1,302 patients across the U.S., Europe, and Asia Pacific.
Professor Mitchell W. Krucoff from Duke University Medical Center, who led the research, highlighted that the new stents significantly reduced the risk of target vessel failure due to ischemia by 31%, and lowered the incidence of adverse cardiovascular events by 45%. This includes a decrease in heart attacks, cardiac deaths, and the need for repeat procedures on the same lesion.
Meanwhile, Professor Patrick Serruys from Erasmus University in the Netherlands emphasized that while the new drug-eluting stents appear safe for up to two years, more long-term data is needed to fully assess their safety and effectiveness. He called for further studies to confirm these promising results and ensure that the benefits observed are sustained over time.
The findings were widely discussed among cardiologists and industry experts, with many viewing the new stent technology as a major advancement in the treatment of coronary artery disease. As the field continues to evolve, ongoing research and real-world application will be crucial in determining the full impact of this innovation on patient care.
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