1. Effects on the cardiovascular system Dippers, tinctures, and decoctions of bone gum have significant antihypertensive effects on intravenous injections of anesthetized dogs, cats, and rabbits, and are accompanied by slower heart rate and faster breathing; It appears to be superior to decoction; repeated administration can produce varying degrees of rapid tolerance. Concentrated tinctures given to anesthetized dogs, cats, intramuscular injections or decoctions to give a non-anesthetized rat gavage also showed a sustained and stable antihypertensive effect The hypotensive effect of Digupi is related to the central nervous system, and it may also have the effect of blocking sympathetic nerve endings and direct vasodilation. During the blood pressure reduction period, ECG showed no significant changes except that the heart rate slowed down and the T wave decreased. Poisoning doses can cause partial or complete block of atrioventricular conduction in the hearts of guinea pigs. 2, hypoglycemic effect of rabbits fed to bone decoction, the first increase in blood glucose for a short time, and then lastingly reduced, 4 to 8 hours has not been restored. There is no obvious antagonistic effect on hyperglycemia caused by the injection of epinephrine. Subcutaneous injections of extracts from rabbits, blood glucose also reduced the extract of another beaked root of axillary roots can cause a significant and sustained reduction in blood glucose in rats, increased carbohydrate tolerance, and its lowering blood glucose effect is due to the presence of deuterium derivative Things. 3. The antipyretic effect of bone skin has a significant antipyretic effect on artificially heated rabbits. The ether extract and the water extract of the residue after ethanol extraction have no effect, while the ethanol extract, water extract or ethyl ether extract after the extraction has a role. Its antipyretic effect is weaker than aminopyrine, about the same as other antipyretics.