Release date: 2007-04-16
Japan develops new substances to kill cancer cells Japanese researchers have developed a compound that emits gamma rays and kills surrounding cancer cells under neutron irradiation.
Researchers at Tohoku University and Kobe College in Japan observed that when cells absorb nutrients, abnormal cells such as cancer cells can absorb larger particles than normal cells. Researchers used this feature of cancer cells to begin research. They use a strontium element that emits gamma rays efficiently, allowing hydrazine to react with a hydrophilic substance in "supercritical water". "supercritical water" means that the temperature and pressure of water rise to 374.3 degrees Celsius and At 220 standard atmospheric pressure or more, a water between the liquid and gaseous intermediate states is formed. The compound particles produced by the reaction are about 40 nanometers in diameter. Such a size makes it impossible to enter normal cells, but can penetrate into cancer cells. Abnormal cells ensure that the next treatment is more targeted.
When experimenting with experimental mice suffering from cancer, the researchers injected the compound into the test mice and confirmed that the compound particles had accumulated inside the cancer cells after about 12 hours. Under neutron beam irradiation, the compound particles emit gamma rays and kill their "host" cancer cells.
Fussen Yoshishin, a professor at the Faculty of Pharmacy at Kobe University, responded by telephone to a reporter from Xinhua News Agency on March 30. Before that, the method of using neutron radiation to concentrate boron to produce alpha rays to kill cancer cells has been widely watched, but The alpha ray effective distance of the method is about 10 microns, and the newly developed bismuth compound emits gamma rays with an effective distance of 100 microns, which is suitable for killing widely spread cancer cells.
Fussen Yixin said that the next topic is to improve the accuracy of the accumulation of this compound particle to cancer cells, completely solve the safety and other issues, and to introduce an efficient and safe new cancer treatment method. ——Midi Medical Network
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