Professor Zeng Nan: Using scientific data to solve "Traditional Chinese Medicine Metaphysics"

In the view of Zeng Nan, a professor at Chengdu University of Traditional Chinese Medicine, traditional Chinese medicine pharmacology is a relatively good combination of Chinese and Western medicine. The theoretical guiding ideology of research relies on the theory of traditional Chinese medicine, and the methods used and explained are based on modern medicine. At the same time, pharmacology of traditional Chinese medicine is also a bridge between Chinese medicine and traditional Chinese medicine, and it also serves as a bridge for the communication between Chinese and Western medicine.

As a professor at Chengdu University of Traditional Chinese Medicine, Zeng Nan has been working in this school for 24 years.

Since her graduation from the master's degree, she has worked in the teaching and research of Chinese medicine pharmacology. In the past 20 years, she has undertaken 7 national projects such as the 85, 95 research projects of the Ministry of Science and Technology, the 973 project, and the National Natural Science Foundation. More than 120 papers, more than 20 textbooks and academic works, the second prize of Sichuan Science and Technology Progress Award, the first prize of Sichuan Province teaching achievements and so on.

At the eleventh party congress in Sichuan Province, she was elected as the party's 19th representative.

“The research work of pharmacology is to use a scientific method to provide a layer of insurance for Chinese medicine.” As an “insurer” of traditional Chinese medicine, Zeng Nan used the quantifiable data in the experiment to break the theory of “Traditional Chinese Medicine Metaphysics” while teaching and educating people. In the post, I have never stopped moving forward.

Pharmacological experiments last for 4 months

At 10:30 on September 30, at the Wenjiang Campus of Chengdu University of Traditional Chinese Medicine, Zeng Nan returned to the office after class and began to guide graduate studies.

"You first look at the liquids of the two samples. Try it today. I will come back to you tomorrow after class." She went over and looked at the work that a male student was doing, and said softly.

In the room of about 20 square meters, there is a large workbench filled with glass beakers of different sizes and other experimental instruments.

The two refrigerators in the corner are filled with various reagents; on the wall, a few photos of her and the students are hanging. Here is a laboratory for traditional Chinese medicine pharmacology at Chengdu University of Traditional Chinese Medicine. In normal times, Zeng Nan is here to communicate with students.

As an experimental subject, animal experiments and cell experiments have become an important part of the research of pharmacology.

"As long as the experiment begins, people need to continue to follow up. If they encounter holidays, they can't rest." Most people are difficult to understand the complexity of the experiment. Zeng Nan said that he told students that they should learn to suffer when they choose pharmacology. During the experiment, if the cycle is long, it may last for 3 to 4 months.

Using scientific data to solve "Traditional Chinese Medicine Metaphysics"

Facing the question of Chinese medicine in the society, she deeply felt the importance of the scientific evidence spirit.

"Compared with the Western medicine ingredients and drug efficacy data, the traditional Chinese medicine theory is relatively macroscopic, and most people sound that it is mysterious, but this does not affect the trust of the majority of patients in traditional Chinese medicine for thousands of years. We defend the dignity of Chinese medicine, that is, Adhere to the spirit of scientific evidence." Zeng Nan believes that there are many factors affecting the efficacy of traditional Chinese medicine. Including the origin, harvesting, storage, processing, process and so on will affect the content of active ingredients, but this is not as fascinating as it is. Her work is to use modern science and technology to describe the effectiveness and safety of traditional Chinese medicine or compound under the guidance of traditional Chinese medicine theory, and to provide scientific connotation for its functional indications.

In her view, quantifiable data analysis eliminates people's misunderstandings and also gives Chinese medicine a safety plug. Let the majority of patients use it with confidence and use it safely.

"For example, ginseng, ordinary people know that it is a blind tonic, traditional effects can make up for the vitality, attending deficiency syndrome. And the work we have to do is to explain why ginseng has this effect, because taking ginseng can improve the body's immunity, can Regulates the body's material metabolism, endocrine system function, etc., so it is suitable for elderly patients with weak syndrome. Generally speaking, we can say that our work is an insurance for Chinese medicine, making it more effective and safe in application." Zeng Nan said .

Standing for 24 years, three feet of podium, Tao Li, the world

In 1990, Zeng Nan took the master's degree in Chengdu University of Traditional Chinese Medicine. In this year, the medical school only enrolled two graduate students, and her pharmacology only "excelled." When you need to do experiments, from beginning to end, purchase reagents, consumables, no matter how far or near, no one delivers, all things have to be personally.

In 1993, after she graduated from graduate school, she stayed as a teacher. Counting this year, it should be the 24th year of entry.

On the three-foot platform, Zeng Nan’s station was 24 years old, facing one after another, new students and one research project after another. Over the years, she has trained more than 40 graduate students.

Just on the teacher's day just past, she received a photo album that she was very touched. Open the photo album, and a pair of familiar faces smile at her. This is the students she has brought before. Some students collected photos of some of their graduated brothers and sisters through various channels, gathered them in the album, and wrote the words of blessings, and gave them to the respected teacher.

Overcoming depression and letting research services clinical

In 2005, Zeng Nan began to study the antidepressant effect of the traditional Chinese medicine classic Xiaoyao San. She has been studying this issue for more than ten years. At present, in terms of antidepressant effects, Zengnan's team has streamlined Xiaoyao Powder from 8 herbs to 3 to 4 drugs, laying a preliminary foundation for the development of an innovative anti-depressant Chinese medicine.

In her view, pharmacology of traditional Chinese medicine is a relatively good combination of Chinese and Western medicine. The theoretical guiding ideology of its research relies on the theory of traditional Chinese medicine, while the methods of use and the mechanism of interpretation rely on modern medicine. At the same time, pharmacology of traditional Chinese medicine is also a bridge between Chinese medicine and traditional Chinese medicine, and it also serves as a bridge for the communication between Chinese and Western medicine.

“Because Chinese medicine is a traditional cultural heritage, the state is investing more and more in the development of innovative products and new drugs for Chinese medicine.” She introduced pharmacology as an indispensable link in the development of new drugs. In the past few years, professional development has remained relatively good.

Over the years, Zeng Nan has profoundly realized the enhancement of the competitiveness of all parties in the research of Chinese medicine. In the past, only Chinese medicine colleges or research institutes were doing Chinese medicine research, and now many comprehensive universities have begun research on Chinese medicine.

"Now, we must try our best to give full play to the outstanding advantages of our Chinese medicine profession, pay attention to the guidance of the theory of traditional Chinese medicine, research from the clinical, and finally return to the clinic and serve the clinic."

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